BPC-157 Dosing Guide
The most common daily-injection peptide for tendon, ligament and gut recovery.
BPC-157 is used mostly for soft-tissue recovery — tendons, ligaments, muscle strains — and for gut issues. The numbers people use are remarkably consistent: a few hundred micrograms a day, every day, for a month or two. The dose is tiny (a tenth of a milligram or less), so the syringe math matters more than with most peptides.
At a glance
- Typical dose
- 250–500 mcg per injection (500 mcg/day is the most-cited total)
- How often
- Once a day, or split into two (morning and evening)
- Route
- Subcutaneous — near the injury or in the abdomen
- Timing
- Any time; many sources suggest morning on an empty stomach
- How long
- 4–8 weeks, then a 2–4 week break
- Vial size
- 10 mg
How much
Across vendor guides, clinic pages and community references, the standard dose is 250 to 500 micrograms (mcg) per injection. The single most-cited figure is 500 mcg per day — taken either as one 500 mcg shot or as 250 mcg twice a day.
The full range reported is about 200 mcg up to 1,000 mcg per day. The upper end is reserved for more serious injuries or post-surgical recovery; nobody routinely cites more than 1 mg a day. A few sources use a ramp (200 → 400 → 600 mcg/day over several weeks), but the flat 250–500 mcg figure is far more common.
How often & when
Once daily is the most common schedule. Twice-daily dosing (roughly 12 hours apart) is the second most common, especially for gut-focused use or in the first weeks after an injury.
Injections go under the skin. Many people inject as close to the injury as is practical (the peptide is thought to act partly locally), while others simply use the abdomen for a systemic effect — both approaches show up in the sources. Morning on an empty stomach is frequently suggested but is not a firm rule.
How long
Most sources describe a course of 4 to 8 weeks, followed by a 2 to 4 week break. Minor injuries are often quoted at 2–4 weeks; serious tendon or ligament injuries at 8–12 weeks. Some guides run 8 weeks on, 8 weeks off.
Commonly quoted timelines: pain relief within 3–5 days, better mobility in 1–2 weeks, structural healing over 4–6 weeks. Treat these as what people report, not as guarantees.
Mixing the vial
Doses below are for a standard U-100 insulin syringe (100 units = 1 mL). The formula: units = dose in mg ÷ concentration in mg/mL × 100. Bacteriostatic water is the usual diluent. A standard peptide vial holds about 3 mL of liquid at most — the store’s vials included — so every row below stays at or under 3 mL. Guides elsewhere that call for 4–5 mL will not fit.
| Vial | Water added | Concentration | Doses in units |
|---|---|---|---|
| 10 mg | 2 mL | 5 mg/mL (5,000 mcg/mL) | 250 mcg = 5 units · 500 mcg = 10 units · 40 doses of 250 mcg per vial |
| 10 mg | 3 mL | 3.33 mg/mL | 250 mcg ≈ 7.5 units · 500 mcg = 15 units |
The 2 mL mix is the dominant convention because the unit math is clean: 1 unit = 50 mcg. At 500 mcg a day, one 10 mg vial lasts 20 days.
How to reconstitute
Not sure how to mix the vial? Our free Reconstitution Calculator walks you through it: enter the vial size, how much bacteriostatic water you're adding and the amount you want per dose, pick your syringe, and it tells you exactly what mark to draw to, the concentration, and how many doses the vial holds — with a syringe diagram and a step-by-step worked example.
Practical tips
- Keep the mixed vial in the fridge (2–8 °C) and use it within about 4 weeks. Never freeze it once mixed.
- Rotate injection sites — abdomen quadrants, thigh, upper arm — and use a fresh syringe every time.
- It is very often paired with TB-500 (the “Wolverine stack”): BPC-157 daily plus TB-500 twice a week. The store sells this pairing pre-blended as BB — see the BB guide, since a fixed-ratio vial is dosed differently.
- If you are mixing your own, the free reconstitution calculator on the tools site checks the units for you.
What the evidence looks like
Evidence level
Almost all of the science is in rodents (the standard rat dose is 10 mcg/kg; the human figures above come from scaling that down). A handful of small human pilot studies exist, but there is no controlled human dose-finding trial, and BPC-157 is not an approved drug anywhere. The doses here are community convention, not a clinical standard.
For what the compound is and how it is studied — mechanism, research history and the primary literature — read the reference entry: BPC-157.
Batch-tested with published COAs
BPC-157 on the store
Every vial is tested by an independent lab, with a batch-linked certificate of analysis you can check before you buy. This page is educational; purchasing happens on the store.
Common questions
How many units of BPC-157 do I draw?
With 10 mg mixed in 2 mL of bacteriostatic water, 5 units on an insulin syringe is 250 mcg and 10 units is 500 mcg.
Do I inject BPC-157 at the injury site?
Many people do, as close as is practical, on the theory that it acts partly locally. Injecting in the abdomen for a whole-body effect is also common. Both approaches appear throughout the sources.
How long does a 10 mg vial last?
About 20 days at 500 mcg a day, or 40 days at 250 mcg a day.
Sources
The figures above were compiled from the following pages. Where an FDA label exists it is listed first; the rest are vendor, clinic and community dosing references, which are not peer-reviewed.
- Peptide Dosing Protocols — BPC-157 — 250 mcg 1–2×/day standard; 4–12 week cycles; 10 mg + 2 mL mixing math Open
- Peptide Deck — BPC-157 dosage guide — 250 mcg twice daily; 4–8 weeks on, 2–4 off; refrigerate 3–4 weeks Open
- The Peptide Catalog — BPC-157 dosing guide — 500 mcg/day standard, 250 mcg maintenance; 8 on/8 off; no human trials Open
- Tucson Wellness MD — BPC-157 dosage guide — 250–500 mcg/day, up to 1,000 mcg for severe injury; local injection for tendon/joint Open
- Peptide Dosages — BPC-157 10 mg vial — 200 → 400 → 600 mcg/day ramp; 3 mL mixing alternative Open